Jim Heath with Jingyi Xie in a conference room

New Research Uncovers Hidden Rules of Immune Response

Scientists at the Institute for Systems Biology (ISB) reveal how T cells "decide" their fate in fighting infections like COVID-19, paving the way for improved treatments for infections, cancer, and autoimmune diseases.

New Research Uncovers Hidden Rules of Immune Response
New Research Uncovers Hidden Rules of Immune Response
recover - researching covid graphic

Understanding, Preventing and Treating Long-Term Effects of COVID: RECOVER Study Enrolling Patients from Pacific Northwest

As part of a massive nationwide effort, ISB is leading a multi-site consortium for the NIH RECOVER (Researching COVID to Enhance Recovery) Initiative. The Pacific Northwest consortium is made up of ISB, Providence, Swedish, and University of Washington School of Medicine.

Understanding, Preventing and Treating Long-Term Effects of COVID: RECOVER Study Enrolling Patients from Pacific Northwest
Understanding, Preventing and Treating Long-Term Effects of COVID: RECOVER Study Enrolling Patients from Pacific Northwest
screenshot of video for Predicting ‘Long COVID’ At Initial Point of COVID-19 Diagnosis

Predicting ‘Long COVID’ At Initial Point of COVID-19 Diagnosis

Researchers have identified several factors that can be measured at the initial point of COVID-19 diagnosis that anticipate if a patient is likely to develop long COVID. They also found that mild cases of COVID-19, not just severe cases, are associated with long COVID. Their findings were published by the journal Cell.

Predicting ‘Long COVID’ At Initial Point of COVID-19 Diagnosis
Predicting ‘Long COVID’ At Initial Point of COVID-19 Diagnosis
screenshot of video for Research Roundtable with Dr. Jim Heath on COVID

Research Roundtable with Dr. Jim Heath on COVID

On January 18, 2022, Dr. Jim Heath gave a talk on COVID at the first Research Roundtable event of 2022. Research Roundtable is a series of ISB hosted conversations with our leading scientists on the latest research happening at ISB. Designed for a lay audience, this series is open to all. Attendees have the opportunity to ask questions directly to our scientists.

Research Roundtable with Dr. Jim Heath on COVID
Research Roundtable with Dr. Jim Heath on COVID
Drs. Jim Heath, Yapeng Su and Jihoon Lee

Metabolic Changes in Plasma and Immune Cells Associated with COVID-19 Severity, May Predict Patient Survival

Researchers from Institute for Systems Biology (ISB), Fred Hutchinson Cancer Research Center and other organizations have uncovered underlying metabolic changes that regulate how immune cells react to COVID-19. These findings are associated with COVID-19 severity and may predict patient survival. The work was published in the journal Nature Biotechnology.

Metabolic Changes in Plasma and Immune Cells Associated with COVID-19 Severity, May Predict Patient Survival
Metabolic Changes in Plasma and Immune Cells Associated with COVID-19 Severity, May Predict Patient Survival
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