Publications

Recent Publications


Keywords:     pan-virus analysis                     conserved host response to viruses                     systems immunology                         multi-cohort analysis               covid-19


Keywords:   GBM    anti-PD1      Tissue imaging        machine-learning based image analysis          immune response


Keywords:   Immune response         multi-omics        COVID-19        infection        proteomics        metabolomics        single-cell TCR-seq        single-cell RNA-seq       CITE-seq        single-cell secretome


Keywords:   Immune response         COVID-19 patients      X Chromosome          genetic risk


Keywords:   Immune response               COVID-19           Type I interferons            autoantibodies


Keywords:   Immune response         multi-omics        COVID-19        infection        proteomics        metabolomics        single-cell TCR-seq        single-cell RNA-seq       CITE-seq        single-cell secretome


Keywords:    Multi-omic     melanoma         cell trajectories       drug-tolerant


Keywords: Raman scattering microscopy     Glycogen    melanoma   metabolism


Keywords: Raman spectro-microscopy     metabolomics   melanoma   lipidomics   transcriptomics


Keywords:  immunotherapy     neoantigen   immunogenomics   epitope   TESLA   immunogenicity


Keywords: Antibiotic resistant     antibody-recruiting protein‐catalyzed capture agents (AR-PCCs)


Keywords: Plasmodium falciparum   HRP2   protein‐catalyzed capture agents (PCCs)


Keywords: T cell activation | PINEM | electron microscopy | electron-photon coupling | T cell receptor


Keywords: hematopoietic stem cell         HSC       TCR       gene therapy       cell therapy       stem cell therapy       cancer immunotherapy       sr39TK suicide gene       preclinical development


Keywords: cancer immunotherapy   nanotechnology   microfluidics    T cell receptor


Keywords:  cancer immunotherapy   nanotechnology   microfluidics    T cell receptor

Protein-Catalyzed Capture Agents

Chemical Reviews, 2019

Keywords:  PCCs   Click Chemistry   Antibodies


Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

J. Clinical Oncology, 2019

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Keywords:  Glioblastoma   Cancer Research    Diagnostics    Translational Medicine


T cell antigen discovery via trogocytosis

Nature Methods, 2019

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Keywords: Immunotherapy     Cancer Research     Single Cell Technologies  Biomolecular Engineering


T cell antigen discovery via signaling and antigen-presenting bifunctional receptors 

Nature Methods, 2019

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Keywords: Immunotherapy     Cancer Research      Single Cell Technologies  Biomolecular Engineering


Surface Immobilization of Redox‐Labile Fluorescent Probes: Enabling Single‐Cell Co‐Profiling of Aerobic Glycolysis and Oncogenic Protein Signaling Activities

Angew. Chem. Int. Ed. Engl., 2018

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Keywords: Glioblastoma      Cancer Research      Single Cell Technologies


Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

Cell, 2018

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Keywords: Cancer Research      Immunotherapy       Computational Methods    Biomolecular Engineering


Allosteric Inhibitor of KRas Identified Using a Barcoded Assay Microchip Platform

Analytical Chemistry, 2018

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Keywords: Cancer Research    Capture Agents    Nanotechnology


Modulating the Folding Landscape of Superoxide Dismutase 1 with Targeted Molecular Binders

Angew. Chemie Int. Ed. Engl., 2018

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Keywords: Neurological Research    Capture Agents    Biomolecular engineering


Epitope‐Targeted Macrocyclic Peptide Ligand with Picomolar Cooperative Binding to Interleukin‐17F   

Chemistry: A European Journal, 2018

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Keywords: Immunotherapy    Capture Agents    Biomolecular engineering


A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication

PLoS One, 2018

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Keywords: Immunotherapy    Single Cell Technologies


Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells are associated with clinical outcomes in NHL

Blood, 2018

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Keywords: Cancer Research     Immunotherapy     Single Cell Technologies


Integrated measurement of intracellular proteins and transcripts in single cells

Lab on a Chip, 2018

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Keywords: Single Cell Technologies


Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response

Journal for ImmunoTherapy of Cancer, 2017

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Keywords: Cancer Research     Immunotherapy     Single Cell Technologies


Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance

Proc. Nat. Acad. Sci, 2017

Keywords: Cancer Research     Immunotherapy     Single Cell Technologies


Future cancer research priorities in the USA: a Lancet Oncology Commission

The Lancet Oncology, 2017

Keywords: Cancer Research     Public Policy